CHEM 705 Synthesis & Reaction Mechanism
This course covers fundamental aspects of writing mechanisms for organic and inorganic reactions. Basic principles and reaction are reviewed with a focus on mechanistic understanding and synthetic applications. In organic part; addition, elimination, substitution, and rearrangement reactions are covered based on polar and radical mechanisms. In inorganic part; ligand substitution reaction mechanisms will be covered for both coordination and organometallic complexes. Inner sphere and outer sphere redox reaction mechanisms and photochemical reaction mechanisms will be covered. In organometallic part; homogeneous catalytic mechanisms and their applications in cross-coupling reactions and C-H activation will be covered. All reactions and mechanisms will be applied in design and retrosynthesis of natural products.